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Substantial Matters: Life & Science of Parkinson’s


In Substantial Matters: Life & Science of Parkinson’s, host Dan Keller, PhD, interviews Parkinson’s experts to highlight treatments and techniques that can help you live a better life now, as well as research that can bring a better tomorrow. Episodes focus topics relevant to your daily life, including new levodopa delivery methods, exercise, clinical trials, nutrition and more! Learn more about our episodes and speakers at parkinson.org/Podcast. Follow and rate us on your favorite podcast platform to be notified when there’s a new episode! Let us know what other topics you would like us to cover by visiting parkinson.org/feedback.

May 28, 2024

Gene-based therapy for Parkinson’s disease is an area of research that is currently being developed. It works by introducing genetic material into the brain, which can then “instruct” cells to produce compounds that can potentially alleviate symptoms of Parkinson’s. Although years have gone by since the first gene-based clinical trial, there is still much to learn before fully realizing its potential impact to treat Parkinson’s disease.

In this episode, Movement Disorders Neurologist, Andrew Feigin, MD of New York University Langone Health discusses what gene-based therapy is, how it differs from cell-based therapy, different trials currently in progress, and considerations for future research.