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Substantial Matters: Life & Science of Parkinson’s

Aug 16, 2017

Driving is a complex task involving many physical skills and mental processes. Age, along with a chronic or progressive illness like Parkinson’s, affects these critical driving skills, making a driver less safe on the road. But giving up the keys is an emotionally charged issue. Lissa Kapust created DriveWise,...


Aug 1, 2017

There are many drugs and therapies for Parkinson’s, but none halt progression of the disease. This is partly because we still do not understand exactly what causes Parkinson’s, so it is hard to figure out how to prevent it or slow it down. One potential target for new therapies is alpha-synuclein, a protein found in...


Jul 18, 2017

For decades, most people with Parkinson’s disease have been able to control symptoms with levodopa and other drugs. But researchers have yet to find a way to protect neurons in the brain to slow down or stop progression of Parkinson’s. Dr. David K. Simon discusses how modern genetics can be a guide to developing new...


Jul 4, 2017

More than 50 years after its discovery, levodopa is still the most effective treatment for Parkinson’s, but some people experience “off” periods or dyskinesias with oral medications. Dr. Mark Guttman describes new delivery methods that promise to help with some of these problems, especially for people who have...


Jun 20, 2017

Parkinson’s can be unpredictable – symptoms can come and go or get better and worse throughout the day. These so-called “on-off” fluctuations (also called motor fluctuations) and dyskinesias can be troubling, but movement disorder specialists can help with the choice of medication, dosages, and timing. Dr. Irene...